Siblings Danny (Johnny Delgado), Art (Edu Manzano) and Grace (Dina Bonnevie) are living their lives separately with their respective families, but when their ailing mother Dolores "Loleng" Rosales (Gloria Romero) is slowly dying of Alzheimer's disease, the parted siblings went back to their ancestral house. Grace is living in the US with her husband Francis (Joel Torre), two children Madeline (Janet McBride) and Andrew (John Prats). They are struggling to maintain US living with their meager salary. Art, on the other hand, is having a high-maintenance lifestyle in Manila with his wife Nanette (Cherry Pie Picache), children John John (CJ Ramos), and Rommel (Jericho Rosales), who he pressures to finish medical school. Meanwhile, Danny, unemployed, is left in their ancestral house to take care of their mother together with his wife Celine (Hilda Coronel), three children Chona (Carol Banawa), Carina (Shaina Magdayao), and only son Boyet (Marvin Agustin), who hates his father for not aiming a better life for them. Danny plans to sell their 80 hectares property and divide the amount with his siblings. However, Art does not agree with the plan. But more than arguing about their property’s settlement, their past sibling rivalries also affected the relationships of the family members. Will they ever settle their differences and past issues? Or, will their mother die failing to witness her children reconcile for real and good?